Download Amobarbital Effects and Lateralized Brain Function: The Wada by David W. Loring, Kimford J. Meador, Gregory P. Lee, Don W. PDF

By David W. Loring, Kimford J. Meador, Gregory P. Lee, Don W. King

The intracarotid amobarbital (or Amytal) process is usually known as the Wada try out in tribute to Juhn Wada, the health professional who devised the strategy and played the 1st simple animal study and scientific stories with this technique. Wada trying out has develop into an essential component of the pre­ operative overview for epilepsy surgical procedure. apparently, notwithstanding, Wada in the beginning built this technique as a method to evaluate language dominance in psychiatric sufferers so that electroconvulsant remedy will be utilized unilaterally to the non-dominant hemisphere. Epilepsy surgical procedure has matured as a achievable therapy for intractable seizures and is not any longer confmed to a couple significant universities and clinical institutes. but, as is more and more transparent by way of interpreting the surveys of techniques utilized by epilepsy surgical procedure facilities (e.g., Rausch, 1987; Snyder, Novelly, & Harris, 1990), there isn't in simple terms nice heterogeneity within the tools used in the course of Wada trying out to evaluate language and reminiscence features, yet there additionally appears an absence of consensus concerning the theoretical assumptions, and maybe, even the ambitions of this procedure.

Show description

Read Online or Download Amobarbital Effects and Lateralized Brain Function: The Wada Test PDF

Similar neurosurgery books

Medical Radiology - Spinal Imaging - Diagnostic Imaging Of The Spine And Spinal Cord

Clinical imaging of the backbone is without doubt one of the most often played diagnostic studiesdue to the excessive occurrence of the quite common medical challenge of acute or chronicback discomfort. Radiologists have a complete diversity of diagnostic modalities at their disposal to studyspine pathology. it's of the maximum significance that they be acquainted with the advantagesand negative aspects of those assorted diagnostic recommendations and may be able to practice, in eachclinical scenario, the tactic that's probably to optimally remedy the scientific problemand point out its right administration.

Spinal disorders: fundamentals of diagnosis and treatment

Spinal problems are one of the commonest health conditions with major impression on overall healthiness similar caliber of existence, use of future health care assets and socio-economic expenditures. this is often an simply readable educating instrument concentrating on basics and simple rules and offers a homogeneous syllabus with a constant didactic method.

Neurology Self-Assessment: Focus on Neuroimaging

This cutting edge case-based question-and-answer examine consultant to neuroradiology is geared to neurology and neurosurgery citizens, scientific scholars, and resident graduates getting ready for the neurology and neuroradiology forums. The e-book offers a hundred and one instances from grownup neurology, pediatric neurology, and neurosurgery perform overlaying all significant neuroradiology themes.

Brain diseases and metalloproteins

This ebook describes the most recent examine on neurodegenerative illness and metal-binding proteins. It lays robust emphasis on biochemistry and mobilephone biology. The ailments lined within the e-book contain Parkinson's illness, Alzheimer's ailment, prion sickness, and ALS. The chapters individually research such concerns as mechanisms of steel binding, metal-induced structural adjustments in proteins, adjustments in mobile steel metabolism in disorder, and makes an attempt at a healing technique according to protein steel binding.

Additional info for Amobarbital Effects and Lateralized Brain Function: The Wada Test

Example text

Seizure onset was lateralized to the left with an initial 6 second left-sided suppression. In the second operation, approximately 2 cm of anterior hippocampus and the entire uncus was removed (Penfield & Mathieson, 1974). Following surgery, the patient displayed a pronounced memory impairment in which Dr. Penfield was reportedly the only hospital staff member correctly identified. In contrast to the initial operation, the second surgery caused no aphasia. One month following surgery, he obtained a FSIQ of 120 (VIQ = 129, PIQ = 107).

Of particular importance from a clinical perspective was the absence of differential memory performance as a function of seizure onset laterality. Fedio & Weinberg stated that their patients did not have abnormal EEG discharges from the hippocampal region; however, depth electrodes were not used. , absence of contralateral/ipsilateral effect), their memory task appears insensitive to bitemporal dysfunction. Engel, Rausch, Lieb, Kuhl & Crandall (1981) administered 125 mg injections to 7 temporal lobectomy candidates and employed a continuous performance/recognition task to assess memory.

Saisa, Silfvenius & Christianson (1990) studied visual half-field testing, but tried to increase its specificity by adjusting the stimulus presentation time to accommodate individual performance differences, as well as presenting some of the stimuli in a "mirrored" orientation. Fourteen of 16 patients were righthanded, and 13 of these had a right visual half-field advantage; 1 right-handed patient performed poorly and without any left or right half-field superiority. The 2 left-handed patients had left visual half-field superiority.

Download PDF sample

Rated 4.09 of 5 – based on 26 votes